Prevalence and predictors of elevated liver enzymes among hospitalized adolescents with anorexia nervosa

ACKNOWLEDGEMENTS • In this largest study of AN and elevated liver enzymes to date, degree of malnutri)on and sex predicted ALT ≥ 40 on admission but ini)al prescribed calories may also be associated with ALT ≥ 40 aJer admission in a small propor)on of pa)ents. • ALT is known to be higher in males than females at baseline; therefore, males may be more likely to present with elevated liver enzymes as in this study • Future research should beMer characterize the evolu)on of elevated liver enzymes in pa)ents hospitalized with AN undergoing refeeding. Study Popula<on • Inclusion criteria: subjects 10-­‐22 years of age with AN, first admiMed to a ter)ary children's hospital from January 2007 to December 2012 • Demographic factors, anthropometric factors, dura)on of illness, ini)al prescribed calories, and alanine aminotransferase levels (ALT) were recorded • Dietary recall and prescribed caloric intake on the first day of the hospitaliza)on were reviewed and recorded by a registered die)cian